Is 1,4-butanediol legal in the US?

1,4 Butanediol is an organic compound that is a colorless viscous liquid. It has a distinct bitter taste, and it is used as a solvent in addition to being used as a recreational intoxicant that has effects similar to alcohol. It can result in cognitive euphoria and suppress anxiety. People caught with large quantities of this drug can be prosecuted for trafficking even if they do not have connections with the criminal underworld and do not deal drugs professionally. If you are charged with 1,4 Butanediol trafficking, it is important to consult an experienced Clearwater drug trafficking attorney. At Hanlon Law, we dedicate ourselves to fighting for the rights of people who have been accused of trafficking in this substance as well as others, such as cocaine, marijuana, and meth.

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If you are being charged with 1,4-Butanediol trafficking, the prosecutor must prove that beyond a reasonable doubt, you knowingly bought, sold, manufactured, imported into the state, or actually or constructively possessed at least one kilogram of 1,4-Butanediol. A conviction can be secured for performing any activity that counts as trafficking with a one-kg mixture that includes 1,4-Butanediol and other substances, whether those substances are licit or illicit. People caught and convicted will face a mandatory minimum sentence. A mandatory minimum sentence is one over which a judge does not have discretion.

If you are caught with one to five kilograms of 1,4-Butanediol, a judge must sentence you to at least three years&#; imprisonment and a $50,000 fine. If you are caught with five to 10 kilograms of 1,4-Butanediol, a judge must sentence you to seven years in prison and a $100,000 fine. If you are found with at least 10 kilograms of 1,4-Butanediol, you will face a mandatory minimum sentence of at least 15 calendar years and a $500,000 fine. It is important to realize that you can face first-degree felony charges even for conspiring with or aiding a person who is trafficking in 1,4-Butanediol.

If you knowingly manufacture or bring into Florida 150 kg or more of a mixture that includes 1,4-Butanediol, and you understand that the probable result of your bringing it into the state is someone else's death, you face the possibility of a capital felony conviction for importation or manufacturing. When you are charged with a capital felony, you are not eligible for parole, and you face the possibility of being sentenced to life imprisonment or even death.

Although it is disturbing to be accused of trafficking, it is important to consult a Clearwater criminal attorney as soon as you realize that you are being investigated. The earlier that we get involved, the sooner that we can get started on a strong defense strategy. Sometimes, law enforcement officers fail to abide by suspects' constitutional and procedural rights. In other cases, there may not really be enough evidence to prove what happened beyond a reasonable doubt. Beyond a reasonable doubt is a tough standard, and one strategy that we may use is raising a reasonable doubt with the prosecutor or the jury by presenting a different account of what happened.

Sometimes it is possible to challenge the evidence being used to prove the prosecutor's case. Fourth Amendment case law can be complicated, but often it provides a method by which to challenge evidence that was seized. Generally, police must have a reasonable suspicion of criminal wrongdoing to make a traffic stop. They must have probable cause to get a warrant to search a home or other structure. When police conduct does not meet the appropriate standard, it may be possible to bring a motion to suppress the evidence that was unreasonably seized. For example, if the police did not have probable cause to search your home, it may be possible to get any evidence of 1,4-Butanediol that was obtained during the search suppressed. On the other hand, if the police were there to investigate a call about, and the drugs were in plain view, it may not be possible to suppress the evidence.

If you are charged with 1,4-Butanediol trafficking in Clearwater, you are looking at the possibility of serious consequences, including prison time and a hefty fine. You may also face the stigma of a criminal record and difficulties finding a job, securing housing, or getting a professional license. Our founder, Attorney Will Hanlon, is dedicated to protecting the rights of the accused. He has represented clients charged with trafficking in substances such as 1,4-Butanediol, cannabis, meth, LSD, and cocaine since and is well versed in all criminal defense strategies. You can call Hanlon Law at 813.228. or complete our online form.

One of four stable isomers of butanediol

Chemical compound

1,4-Butanediol, also called Butane-1,4-diol (other names include 1,4-B, BD, BDO and 1,4-BD),[5] is a primary alcohol and an organic compound with the formula HOCH2CH2CH2CH2OH. It is a colorless viscous liquid first synthesized in via acidic hydrolysis of N,N'-dinitro-1,4-butanediamine by Dutch chemist Pieter Johannes Dekkers, who called it "tetramethylene glycol".[6][7]

Synthesis

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In industrial chemical synthesis, acetylene reacts with two equivalents of formaldehyde to form butyne-1,4-diol. Hydrogenation of butyne-1,4-diol gives butane-1,4-diol.[8] It is also made on an industrial scale from maleic anhydride in the Davy process, which is first converted to the methyl maleate ester, then hydrogenated. Other routes are from butadiene, allyl acetate and succinic acid.

A biological route to BD has been commercialized that uses a genetically modified organism.[9] The biosynthesis proceeds via 4-hydroxybutyrate.

Industrial use

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Butane-1,4-diol is used industrially as a solvent and in the manufacture of some types of plastics, elastic fibers and polyurethanes. In organic chemistry, 1,4-butanediol is used for the synthesis of γ-butyrolactone (GBL). In the presence of phosphoric acid and high temperature, it dehydrates to the important solvent tetrahydrofuran.[10] At about 200 °C in the presence of soluble ruthenium catalysts, the diol undergoes dehydrogenation to form butyrolactone.[11] It is used to synthesize 1,4-Butanediol diglycidyl ether which is then used as a reactive diluent for epoxy resins.[12]

1,4-Butanediol is used in the production of polybutylene terephthalate (PBT) plastic.[13]

World production of butane-1,4-diol was claimed to be about one million metric tons per year and market price is about US$ 2,000 (&#;1,600) per ton (). In , worldwide production was claimed to be billions of pounds (consistent with approximately one million metric tons).[14]

Almost half of it is dehydrated to tetrahydrofuran to make fibers such as Spandex.[15] The largest producer is BASF.[16]

Use as a recreational drug

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Butane-1,4-diol is also used as a recreational drug known by some users as "Bute"[17], "One Comma Four", "Liquid Fantasy", "One Four Bee" or "One Four B-D-O".

Some federal courts in the USA have stated that 1,4-butanediol exerts effects similar to its metabolite gamma-hydroxybutyrate (GHB), but several other federal courts have ruled that it does not.

Pharmacokinetics

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Butane-1,4-diol is rapidly converted into gamma-hydroxybutyric acid by the enzymes alcohol dehydrogenase and aldehyde dehydrogenase, and differing levels of these enzymes may account for differences in effects and side effects between users.[18] While co-administration of ethanol and GHB already poses serious risks, co-administration of ethanol with 1,4-butanediol will interact considerably and has many other potential risks. This is because the same enzymes that are responsible for metabolizing alcohol also metabolize 1,4-butanediol so there is a strong chance of a dangerous drug interaction.[18][19] Emergency room patients who overdose on both ethanol and 1,4-butanediol often present with symptoms of alcohol intoxication initially and as the ethanol is metabolized the 1,4-butanediol is then able to better compete for the enzyme and a second period of intoxication ensues as the 1,4-butanediol is converted into GHB.[18]

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Pharmacodynamics

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Butane-1,4-diol seems to have two types of pharmacological actions. The major psychoactive effects of 1,4-butanediol are because it is metabolized into GHB; however there is a study suggesting that 1,4-butanediol may have potential alcohol-like pharmacological effects on its own.[19] The study arrived at this conclusion based on the finding that butane-1,4-diol coadministered with ethanol led to potentiation of some of the behavioral effects of ethanol. However, potentiation of ethanol's effects may simply be caused by competition for the alcohol dehydrogenase and aldehyde dehydrogenase enzymes with co-administered 1,4-butanediol. The shared metabolic rate-limiting steps thus leads to slowed metabolism and clearance for both compounds including ethanol's known toxic metabolite acetaldehyde.

Another study found no effect following intracerebroventricular injection of butane-1,4-diol in rats.[20] This contradicts the hypothesis of butane-1,4-diol having inherent alcohol-like pharmacological effects.

Like gamma-hydroxybutyric acid, butane-1,4-diol is safe only in small amounts. Adverse effects in higher doses include nausea, vomiting, dizziness, sedation, vertigo, and potentially death if ingested in large amounts. Anxiolytic effects are diminished and side effects increased when used in combination with alcohol.

Legality

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While butane-1,4-diol is not currently scheduled federally in the United States,[21] a number of states have classified 1,4-butanediol as a controlled substance. Individuals have been prosecuted for possession of 1,4-butanediol under the Federal Analog Act as substantially similar to GHB.[22] A federal case in New York in ruled that 1,4-butanediol could not be considered an analog of GHB under federal law,[23] but that decision was later overturned by the Second Circuit.[24] A jury in Federal District Court in Chicago found that 1,4-butanediol was not an analog of GHB under federal law, which was not disputed on the case's appeal to the Seventh Circuit Court of Appeals, however this finding did not affect the outcome of the case.[25] In the United Kingdom, 1,4-butanediol was scheduled in December (along with another GHB precursor, gamma-butyrolactone) as a Class C controlled substance. In Germany, the drug is not explicitly illegal, but might also be treated as illegal if used as a drug. It is controlled as a Schedule VI precursor in Canada.

contamination of Bindeez toy

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A toy called "Bindeez" ("Aqua Dots" in North America) was recalled by the distributor in November because of the presence of butane-1,4-diol. The toy consists of small beads that stick to each other by sprinkling water. Butane-1,4-diol was detected by GC-MS.[26] The production plant seems to have intended to cut costs by replacing less toxic pentane-1,5-diol with butane-1,4-diol. ChemNet China listed the price of butane-1,4-diol at between about US$1,350&#;2,800 per metric ton, while the price for 1,5-pentanediol is about US$9,700 per metric ton.[27]

poisoning at Darmstadt Technical University

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In August , several people fell severely ill after consuming drinks at building L2.01 at the Lichtwiese Campus of Darmstadt Technical University, Germany. Seven showed severe symptoms, two were transported to a hospital in Frankfurt am Main, and a 30-year-old person was, for a time, in a critical state. Butane-1,4-diol had been detected in milk packages, as well as in water filters. At the location, detectives also found bromophenols and dicyclohexylamine.[28]

See also

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References

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